E4S Enzyme

GMP Grade E4zyme AS is an aseptically filled, lyophilized mixture of 60% purified class I (C1) and 40% purified class II (C2) collagenase from Clostridium histolyticum pre-mixed with neutral protease from Bacillus polymyxa. CIzyme AS can be used for isolating adipose derived stromal cells from human lipoaspirate.

• Manufactured for superior lot-to-lot enzyme consistency for improved performance consistency
• Optimal enzyme activity (28-42 Wünsch Units) and neutral protease activity (220,000 – 340,000 NP units) per vial to dissociate approximately 100 grams of human adipose tissue.
• Low contaminating endotoxin levels (＜25 EU/OD)
• White lyophilized cake under vacuum in amber bottle sealed with butyl rubber stopper
• Stable for at least 2 years when stored at 2-8 ℃
• Lyophilized in a buffer containing calcium to ensure enzyme stability during initial reconstitution.